In 1957, Fred Crane discovered a substance in the mitochondria of a beef liver - the Coenzyme Q10 or CoQ10. Also called the powerhouses of cells, the mitochondria create energy for the cells. And, for this to happen, CoQ10 is required. Since the substance is essential for energy production among cells, it can be found in every cell of the body. However, higher levels of the substance can be found in organs that are highly active, and one of these organs is the heart. For the heart to function properly, it needs a lot of energy, so it needs high levels of the substance. For this, CoQ10 and cardiovascular health are associated with each other.
Several decades after CoQ10 was discovered, so many studies have proven its importance in people's health, especially their cardiovascular health. One of the most recent CoQ10 studies that have made an impact on cardiovascular health is "The effect of coenzyme Q10 on morbidity and mortality in chronic heart failure" or Q-SYMBIO. The study, led by Svend Aage Mortensen, was presented at the Heart Failure 2013 meeting in Lisbon, Portugal. The results of the study showed that CoQ10 improves heart mortality among patients with moderate to severe heart failure. In the study, which involved 420 patients from different countries, each patient is either given CoQ10 supplementation or placebo. The results showed that there was a decrease in the incidence of major adverse cardiovascular events (MACE) in patients who received CoQ10 supplementation: 14% or 29 patients in the group that received the supplementation compared to 25% or 55 patients in the group that received placebo.
Why is this study so important? It is because heart failure patients usually take statins, which are found to cause CoQ10 deficiency. Deficiency of the substance means there is not enough energy that the heart requires to function properly.
Another cardiovascular health issue that is associated with the substance is heart damage caused by chemotherapy. Several studies found that the substance may help prevent damage caused by certain chemotherapy drugs. In addition, one study found that introducing the substance before heart surgery may reduce damage caused by free radicals and strengthen heart function.
Coenzyme Q10 or CoQ10 is indeed an indispensable substance in maintaining a person's cardiovascular health. Natural sources of the substance include meat, fish, and vegetable oils. CoQ10 for cardiovascular health supplements are also available, and they should help supply the right levels of CoQ10 the body needs to function properly.
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